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New research has suggested more specific means of inhibition may be achieved by preventing MAPK substrate docking [10], [11].
And various animal studies on EAE suggested that the disease severity could be correlated with alteration of BBB integrity, whereas limitation of the disease could be achieved by preventing BBB alterations in EAE [26], [27].
This goal can be achieved by preventing the progression of renal disease and implementing strategies for early detection and optimal treatment of causative diseases.
It is well known that, in economic terms, the main advantage of measles vaccination is represented by the savings that may be achieved by preventing measles cases [ 23, 25, 26].
Such findings also have direct implications for the conservation and restoration of Pritchardia in Hawai'i, by suggesting that restoration will best be achieved by preventing seed predation or by outplanting seedlings.
In contrast, those who lean more toward a Rational/Industrial world-view will tend to see a good life for animals as (primarily) a healthy life, to be achieved by preventing disease and avoiding other vicissitudes of nature.
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Mechanistic studies suggest that metastasis inhibition and survival increase were achieved by preventing the dissemination of viable tumor cells from the primary tumor.
Gene knockdown is achieved by preventing cells from making a targeted protein.
This is achieved by preventing the activation of nuclear transcription factor-kappa-B (NF-κB) (reviewed in [ 4]).
Silencing through DNA methylation is achieved by preventing the binding of distinct transcription factors, or by recruiting methyl-binding proteins, thereby generating a repressed chromatin environment.
In India, vector control measures in urban settings are based primarily on larval source management, which is achieved by preventing ovipositioning by An. stephensi in artificial water storage containers.
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