Sentence examples for be able to downregulate from inspiring English sources

Therefore, the new participant has to be able to downregulate the Mcl-1 to overcome the weakness of BTZ and to achieve a complementary effect.

Several milk peptides were found to be able to downregulate neonatal immune activity, suggesting that they may promote neonatal immune competence.

Other miRNAs, such as miR-15 and miR-16, have been reported to be able to downregulate Bcl-2, a proto-oncogene overexpressed in many type of cancers, leading to a prevention of apoptosis [ 4, 5].

Both bFGF and VEGF, which are the strongest mitogenic factors for endothelial cells, but also other growth factors, such as epidermal growth factor (EGF) and placental growth factor (PlGF) were found to be able to downregulate ICAM-1 though ICAM-1 thoughxtont—on the surface of endothelesserextent onithe (Fig.  1b).

Delivery of survivin siRNA in vivo is still technically challenging, but the application of polyethylenimine (PEI /siRNA complexes have been shown to be able to downregulate survivin in mice and have yielded promising therapeutic results in animals transplanted with glioma cells [ 64].

By being able to downregulate proapoptotic molecules, such as c-abl, cells can evade apoptosis and continue to proliferate.

Nevertheless, bFGF does not affect the chondrogenic and osteogenic potential of TCs and the expression of tendon specific markers, while it was able to downregulate the OCT4 expression.

The endotoxin was able to downregulate a number of genes in a GR-dependent manner.

However, B. infantis is able to downregulate the cytokine induction profile from some gastrointestinal pathogens [53].

These results indicate that miR-148 is able to downregulate Mitf expression by binding to the 148/152B binding site.

If the representative miRNA was able to downregulate via the binding site, it indicates that the other potential miRNAs may also be able to regulate Mitf expression.