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Thus, targeting PDK1 may be a valuable anticancer strategy that may improve the efficacy of chemotherapeutic strategies in breast cancer patients.
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The proposed structures may be a valuable target for anticancer agents directed against telomeres.
In this setting, MMP inhibitor therapy may prove to be a valuable component of the anticancer armoury, and confirmatory trials of this novel agent are warranted.
EEAA shows a strong anti-angiogenic potential in both in vitro and in vivo systems, and we suggest that EEAA may be a valuable herbal source for anticancer drug development.
Taken together, these findings suggest that CAPs with anticancer activity may be a valuable addition to the medical oncologist's armamentarium.
Tumour-targeted functional inhibition of Pms2 may be a valuable strategy for increasing the efficacy of anticancer agents in the treatment of p53-mutant cancers.
The gene-drug correlations using NCI program in these study may be a valuable tool for the identification of determinants of anticancer drug activity in tumors and for the design of cancer chemotherapy.
We believe that it would be a valuable resource and framework that would facilitate novel discovery of potential selective anticancer therapy based on synthetic lethality.
Clinical trials featuring blocking of PD-1-expressing cells (using an anti-PD-1 antibody) to enhance anticancer immune reactions are currently underway; this may be a valuable therapy for lung cancer and melanoma, overcoming immune resistance.
In conclusion, CPTH6 could be a valuable agent for the treatment of cancer and should be further developed as a potent anticancer agent, not only by inducing apoptosis but also by affecting autophagy.
TIPdb-3D is expected to be a valuable resource for the analysis of 3D-QSAR and structure-based virtual screening of bioactive compounds for anticancer, antiplatelet and antituberculosis activities.
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