Sentence examples for be a valid target from inspiring English sources

Consequently, RIPK1 activity might be a valid target in the development of novel therapies for chronic inflammatory diseases.

Our work with the GLI1 inhibitor GANT58 suggests that this pathway may be a valid target for translational research in Ewing Sarcoma.

Since thiazole antibiotics suppress the expression and the activity of FoxM1 and at the same time FoxM1 overexpression protects cancer cells from Siomycin A and thiostrepton toxicity, FoxM1 may be a valid target of thiazole antibiotic-induced apoptosis.

Similarly, VAR F1L may be a valid target for development of antiviral therapeutics.

IL-1 plays a key role in disc degeneration and could be a valid target for inhibiting this process.

Microvascular recruitment may indeed be a valid target for resuscitation in patients with septic shock [ 21, 22].

In addition, disulfide-linked dimers are as active as the monomeric enzyme indicating that the crystal structure of the protein is a valid target for inhibitor design.

Moreover, our studies show that Hz is a valid target for the development of new antimalarials able to overcome CQ resistance.

Finally, treatment with Nrf2 inducers, including 4-OI, sufficiently reduces STING-dependent release of type I IFNs from SAVI-derived fibroblasts promoting the idea that Nrf2 is a valid target in STING-associated inflammatory disorders.

The use of both oseltamivir and zanamivir in clinics has proved that influenza NA is a valid target, and the significance of viral resistance is yet to be seen.

In conclusion our results indicate that TcPTP1 is of importance for cellular differentiation and invasivity of this parasite and thus is a valid target for the rational drug design of potential antibiotics directed against T. cruzi.