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In our earlier work, 18FDG PET-CT imaging of atherosclerotic plaque was found to be a valid prognostic tool to predict patients to whom stroke or ischaemic attacks are more likely to happen within 90 days from the first onset event [3].
Osseous lesions also proved to be a valid prognostic factor (P=0.042; HR 2.046).
Taken together, our results do not support the concern that OPN serum levels might not be a valid prognostic parameter in patients with acute kidney injury undergoing RRT.
Although shown repeatedly to be a valid prognostic predictor, the CCI itself is based on simple assumptions about mortality risk when various conditions co-occur.
The 6MWT was chosen because it requires minimal infrastructure and personnel to complete, has been demonstrated to be a valid prognostic tool for patient outcomes among cardiac surgery patients, 12 57 and is comparable to an exercise stress test.
The 6-months landmark strategy was chosen by our study group, because 6 months were already explored to be a valid prognostic parameter for patients' outcome in previous studies (Heng et al, 2011; Seidel et al, 2012), while 3 months roughly implies the time period from treatment initiation to first treatment evaluation (median: 2.75 months in our analyses).
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Nonomura et al. concluded that the number of MCs infiltrating around cancer foci in prostate biopsy specimens is a valid prognostic factor of prostate cancer.
As depletion of nutritional reserves and a subsequent significant weight loss can lead to an increased risk of morbidity, reduced chemotherapy response, and shorter survival in patients with cancer, TTR is a valid prognostic marker [ 28].
Although it remains to be fully established whether HER2 is a valid prognostic factor in gastric cancer, some studies have suggested that HER2-positivity is associated with poor outcomes and more aggressive disease [ 2, 5, 6, 10], whereas others have shown HER2 to be a favorable prognostic factor [ 11].
Although the 2012 EASL-EORTC Clinical Practice Guidelines [ 12] mention that portal hypertension is a valid prognostic factor in patients undergoing resection in Asia [ 10], most cirrhotic patients in these studies have an etiological background of hepatitis C virus (HCV) and alcohol, rather than HBV (Table 5).
Tumor cell detection in bone marrow can be considered a valid prognostic parameter in patients with early disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com