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If properly selected (based on previous empirical evidence and current scientific theory), an adequately powered subgroup analysis can be a valid hypothesis testing endeavour.
Accepting the concept of a multifactorial set of causes seems to be a valid hypothesis, as this would help explain why the BEN aetiology has been so difficult to decipher for >50 years.
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If escalation, or predator-driven evolution, is a valid hypothesis, there should be a correlation between the diversity and/or abundance of shell-breaking and drilling predators and the degree of defensive ornamentation and armoring of prey species.
The observability analysis of this model is first performed by assuming that a third order ECKF has to be designed, by neglecting the mechanical equation of the IM model, which is a valid hypothesis when the motor is operated at constant rotor speed.
The use of an exponential fitting -as suggested in some references- is a valid hypothesis only if we include infant patients.
Whether intracellular and canalicular trafficking of bile may be altered in ASH is a valid hypothesis.
Thus, flight stabilization is a valid hypothesis, but it needs to be tested by suitable experiments before further conclusions can be drawn.
When the normal approximation is a valid hypothesis, there is a general consistency between the two-sided 95% confidence interval approach (non-inferiority at α/2 < 2.5%) and the non-inferiority chi-square (D-value < 5%), as shown in Figure 1.
Although there is the potential issue of multiple testing, this study is still a valid hypothesis generating study.
The lack of sexual dimorphism in some dendrobatid populations suggests that sexual selection is not a valid hypothesis of the changing coloration.
Thus, the EMH must logically be discarded, as a valid hypothesis must be testable.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com