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The results reported here suggest that PrPC may not be a universal mediator of Aβ synaptotoxicity.
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Based on these recent in vitro observations regarding Atg5 deletion in cells and our in vivo observations regarding Atg7 deletion in the pancreas, it is tempting to speculate that a rise in ROS levels may be a universal downstream mediator of the positive or negative alterations seen in autophagy deficient tissues.
That may be a universal impulse.
Tsatsaronis, J. A., Franch-Arroyo, S., Resch, U. & Charpentier, E. Extracellular vesicle RNA: a universal mediator of microbial communication?
Ca2+ is a universal second messenger that acts as a mediator of stimulus response coupling in eukaryotes.
"That's a universal theme".
"Doodling is a universal behavior.
This is a universal law.
"It's a universal fear.
This is a universal deal.
"Music is a universal language.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com