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The CHRNA4 1674+11C>T polymorphism may be a susceptibility factor for epilepsy, and its higher frequency in patients with juvenile myoclonic epilepsy suggests that the CHRNA4 may be one of the candidate genes for this epileptic syndrome.
Genetic polymorphism in OAS3 gene has been reported to be a susceptibility factor in many infected diseases, but evidence of its effect on enterovirus 71 (EV71) infection is still lacking.
Interestingly, α2M has been proven to be a susceptibility factor in Alzheimer's disease, and as our findings imply, it may also play a relevant role in other neurodegenerative disorders, including prion diseases.
Our microarray data suggests that alterations in elastic fibers and associated microfibrils, a major component of the ECM in the lamina cribrosa, may be a susceptibility factor predisposing the remodeling of the ONH in response to elevated IOP in glaucoma in the AA population.
However, our findings suggesting that TT genotype can be a susceptibility factor are not entirely surprising, given the recent observations.
This data suggests that mild PNPO deficiency could be a susceptibility factor for genetic generalized epilepsies presenting at various ages.
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Decreased [Ca2+]ER is a susceptibility factor for ER stress (Cunha et al. 2008; Cardozo et al. 2005).
This study was designed to investigate sequence variants of the SP110 gene in Chinese and test whether the SP110 gene is a susceptibility factor for tuberculosis.
To test the hypothesis that alterations in the Mediterranean fever (MEFV) gene are a susceptibility factor for the development of polyarteritis nodosa (PAN) we investigated the prevalence of MEFV mutations in patients with PAN without any symptoms of familial Mediterranean fever (FMF).
Mutations in HtrA2 are a susceptibility factor for PD (PARK13 locus) and loss of function models in mice display a neurodegenerative phenotype resembling parkinsonism.
Epstein Barr virus (EBV) is a susceptibility factor to HD.
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