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Based on homology to a yeast protein, ELP1, and co-purification with human Elongator [13], IKAP is thought to be a subunit of the Elongator complex, which assists RNA polymerase II in elongation of transcription in the nucleus [13], [15], [16].
Following BLAST searches, this protein appears to be a subunit of the molybdopterin synthase enzyme, which synthesises molybdenum cofactor (MoCo).
L7Ae has further been shown to be a subunit of archaeal RNaseP [54] required for tRNA maturation.
For example, the BTB/POZ domain-containing protein KCTD12, which may be a subunit of the GABA-B receptor, was observed.
As YAF9 is necessary for H2A.Z deposition in yeast [ 5, 30], it is assumed to be a subunit of the Arabidopsis SWR1-C.
Additionally, because Ku has been reported to be a subunit of human telomerase, future studies could also explore whether human cells use a similar strategy.
Similar(47)
A module is a subunit of the total system.
Kabututu, Z.P., Thayer, M., Melehani, J.H. & Hill, K.L. CMF70 is a subunit of the dynein regulatory complex.
Callegari, S. et al. TIM29 is a subunit of the human carrier translocase required for protein transport.
Kang, Y. et al. Sengers syndrome-associated mitochondrial acylglycerol kinase is a subunit of the human TIM22 protein import complex.
Wang, Y. et al. LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.
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