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If the second molecule is chemically different, there can be a substantial change in the luminescence.
To truly change the nation's chronic overuse of medical care, there will have to be a substantial change in the way patients think about health care, how medicine is practiced and how it is paid for, economists and doctors say.
4.26pm BST If there were to be a substantial change to the UK's current stance that there will be no military intervention in Iraq, Hague says, he's sure he will be back in front of MPs to explain or ask for permission.
"The truth of the matter is that in order for there to be a substantial change either consumers have to change their habits — which we're encouraging through alternative tax of automobiles — or there has to be an increase of supply," he said in the interview.
Responding to yesterday's investigation by The Independent into the crisis in maternity care, Nigel Edwards, the acting chief executive of the NHS Confederation, representing NHS trusts, said: "There is a broad consensus that there needs to be a substantial change in the provision of maternity services involving the downgrading or closure of smaller units to provide safer services.
It is more likely to be a substantial change to an already challenging working environment, in the air as well as on the ground.
Similar(48)
"This is a substantial change in the administration's commitment to Sierra Leone.
The new 35-meter-turning-radius skis are a substantial change from last season's 27-meter variety.
Mr. Clinton said that after the announcement late Wednesday that no agreement had been reached, there had been a substantial change of mind.
"If there's a substantial change in the economic outlook in either direction, then there would be a change in the outlook," Mr. Bernanke said.
Also happening at the same time, I can see, is a substantial change in the way readers are receiving the fiction I write.
More suggestions(20)
be a substantial shift
be a notable change
be a massive change
be a large change
be a great change
be a huge change
be a remarkable change
be a major change
be a considerable change
be a fundamental change
be a tremendous change
saw a substantial change
be a good change
be a big change
be a substantial obstacle
be a substantial portion
be a substantial defection
be a substantial departure
be a substantial limit
be a substantial contribution
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com