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Regarding preemptive treatment, immunological assessment of IFN-γ produced by CMV-specific CD8+ T cells and NK cell function as mentioned in virulence section might be a strong trigger to start preemptive treatment for detected CMV, because there is evidence that impaired CMV-specific CD8+ T cells IFN-γ production prior to CMV reactivation predicts poor outcome, which favors treatment.
These environmental components elevate the serum IgE levels, which can be a strong trigger of infiltration by T cells, eosinophils, mast cells, macrophages, and keratinocytes [ 2].
Recent data indicate that fusion events were increased about 10 to 100-fold in liver, brain and intestine in chronic inflammatory conditions [ 21- 23] suggesting that inflammation might be a strong trigger for cell fusion.
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HMPV appeared to be a stronger trigger for asthma exacerbation than RSV or influenza (Table 2).
Y. enterocolitica is also known to cause granulomatous disease and thus may be a stronger trigger for subsequent immune dysregulation [ 32].
This suggests that substrate is a strong trigger for or may influence metabolite production.
T cell receptor (TCR) activation is a strong trigger for autophagy in T lymphocytes.
"Emotions are far more ancient than cognitive processes" (Wilson 2002, 42), and the perception of racial difference is a strong trigger of in-group/out-group emotional responses in people (Hogan 2009).
Sepsis is a stronger trigger for pNGAL elevation.
An episode of heavy exercise, such as a training drill, can be a strong cardiac triggering factor especially among the physically inactive [ 49, 50].
Thus, a reduction in the recruitment of inflammatory monocytes together with an increase in AAM Фs in the colon may be a strong anticolitic mechanism triggered by T. crassiceps infection.
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