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In some studies, LBP patients with MC have been suggested to be a specific subgroup of LBP [ 2, 22- 24].
Erosive OA appears to be a specific subgroup of hand OA with worse clinical and structural outcomes.
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Despite the very low number, missing values are a specific subgroup and was analyzed separately.
The latter is a specific subgroup of proteins involved in vacuolar protein sorting.
When we compared data from Q-fever patients with the NCSI norm group of COPD patients it should be realized that this is a specific subgroup of COPD patients with a severely impaired health status in multiple sub-domains.
Gene expression profiling data suggest that medullary breast tumors (a rare histological subtype with a prominent lymphocytic reaction and a good prognosis) are a specific subgroup within the basal-like class, indicating that the overall poor survival of basal-like breast cancer might be mitigated in cases in which there is a strong immune response [ 33- 35].
However, this is unlikely to affect the conclusion drawn from the current study, since the errors in coding are unlikely to be focused on a specific subgroup of patients and instead would be expected to be distributed across the whole AF population in the UK.
This as yet untested approach may also lead to individualised strategies based on the fact that a treatment that is helpful to many patients may not be suitable or may even be harmful in a specific subgroup [ 57].
First, involuntary referrals may represent a specific subgroup that is more prone to substance misuse.
Furthermore, even if the relative treatment effect would be higher in a specific subgroup, than still the absolute gain (which determines the cost-effectiveness) would be limited due to the low baseline risk for events without tiotropium treatment occurring in our real-world population.
In line with this conclusion, the described LRR subfamilies could be assigned to a specific subgroup of eukaryotes or prokaryotes, and share similar functions and cellular locations [3].
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