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However, none of these biomarkers was shown to be a specific predictive factor of cisplatin efficacy.
None of these biomarkers was shown to be a specific predictive factor of cisplatin efficacy.
Our results indicate that in postoperative patients prior to the onset of any clinical deterioration PCT may be a specific predictive marker and IL-6 may be a sensitive predictive marker for sepsis.
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Although the presence of KRAS mutations is a specific predictive biomarker for lack of anti-EGFR moAbs efficacy [6] [9], [14], [37] there is convincing evidence that additional genetic events are involved in this process, since approximately half of the KRAS wt patients are resistant to such a treatment [38].
Total number of exercises per session in the HEP is a specific predictive factor for frequency adherence.
The additional and earlier finding that the serum and urine NGAL levels were strikingly elevated in children with AKI after cardiopulmonary bypass [ 35] suggests that NGAL might be a specific, and highly predictive early biomarker for AKI also in humans.
TFF3 is a specific and sensitive predictive biomarker of response to endocrine therapy, degree of response and duration of response in unstratified metastatic breast cancer patients (P=0.000, P=0.002 and P=0.002 respectively).
16 In clinical trials of alkylator-based chemotherapy regimens for glioblastoma, anaplastic astrocytoma, and oligodendroglioma, 9, 18 the MGMT promoter methylation status has proven to be a prognostic, though not a specific predictive biomarker.
A Process Performance Model is a specific type of Calibrated Predictive Model that uses Process Performance Baselines (at least 2) to establish and quantify the relations between Measures.
Since there are no specific predictive clinical signs in sepsis, it would be helpful to have a biological tool to predict the progression of the disease but also to understand the pathophysiology and especially the immune status of the patients.
At present, there is no specific predictive or prognostic marker for OS (Gorlick et al, 2003).
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