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The reason may be a specific effect of sleep deprivation on mechanisms of central sensitization, as suggested by studies on healthy volunteers [20].
Our data suggests that there may be a specific effect of incident TB after ART initiation on immune recovery.
Furthermore, the increase in RelB levels was found to be a specific effect of Tat, as RelB was not increased by treatment with another HIV viral protein, gp120 (Figure 4D).
Increased Ets-1 expression was found to be a specific effect as the protein levels of two similar Ets family members, Ets-2 and PEA3 were not altered in this model of Ets-1 over-expression (Figure 2).
This data suggests while there may be a specific effect of APAP on several genes up-regulated by IFN-β, the predominant effect is a broad, small depression of transcription.
It is possible that the restriction of electron transport between QA of PSII and P700 of PSI in pgr7 affects both linear and PSI cyclic electron transport, but unlike pgr5 [9] there does not seem to be a specific effect on PSI cyclic electron transport.
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The block to development was prevented by co-injection of c-Fyn mRNA with the dominant-negative construct indicating that it was a specific effect.
Such an increase in headache has not been demonstrated for glatiramer acetate [21], underlining the theory that it is a specific effect of interferon beta which is causal for the increased headache frequency.
Whether this was a specific effect on chronic fatigue or a general effect on anxiety was unclear.
This was a specific effect, only observed for a condition requiring emotional prosody discrimination, and not for a condition that required discriminating emotional semantics.
It is therefore of high priority to find out whether this is a specific effect of VEGF-inhibitors or a common theme also for other antiangiogenic strategies.
More suggestions(15)
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Justyna Jupowicz-Kozak
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