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Thus, the down-regulation of ER folding activities in response to osmotic stress may be a specific cellular response of plant cells.
Very high expression level of COL1A2 in both Top-resistant cell lines suggests that expression of this collagen can be a specific cellular response to Top treatment.
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Additionally, we found that ABI3 expression induces senescence, determined by positive results of SA-β-gal staining, which is a specific cellular senescence marker.
However, during the first 1-3 days of sulfur deprivation, there may be a specific increase in the cellular contents of starch (Hemschemeier et al., 2008).
Several authors have suggested that sucrose is a key factor involved in cell division and that there must be a specific mechanism for sensing cellular sugar levels in plants, to control the cell cycle [ 65].
Thus, the observed antiproliferative activity of the most potent compounds in the series is not due to non-specific cytotoxicity but must be attributed to a specific cellular target and is selective towards human prostate carcinoma cells.
We identified NS1 and M1 proteins as the main actors in the remodeling of the host ultra-structure and our results suggest that each influenza A virus strain could be associated with a specific cellular fingerprint, possibly correlated to the functional properties of their viral components.
Microarray analysis offers a variety of methods allowing, among other, identification of genes which might be significant in a specific cellular response mechanism or a particular gene expression pattern that characterizes a particular disease.
Because ChIP-seq is increasingly used for inferring gene regulatory networks, and is also used to validate predictions of other methods [ 48], it is important to understand to what extent ChIP-seq data are limited to a specific cellular context.
Although considerable evidence has indicated that various xenobiotics may be immunosuppressive, little attention has been directed toward ascertaining a specific cellular locus which could be responsible for the impaired immune responsiveness.
Eighty proteins are active in a specific cellular compartment other than the cytoplasm.
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