Sentence examples for be a specific agonist from inspiring English sources

The specificities of these two ligands differ; Protein S was reported to be a specific agonist for TYRO3, while in cells that co-express TYRO3, Protein S is also a potent MERTK agonist [ 7].

Capsaicin, which is lipid soluble and hence able to penetrate the skin, is a specific agonist for the TRPV1 ion channel, expressed by many C-fibers [17].

KA is a specific agonist of the KA receptor and a selective ionotropic glutamate agonist.

We used human TNF because it is a specific agonist for murine TNFR1 and does not act on TNFR2.

Capsaicin is a specific agonist of TRPV1 channels and dose dependently induced calcium influx in endothelial cells and in freshly isolated mesenteric arteries [ 17, 20].

In 2007, Oka et al. (2007) showed that LPI was a specific agonist for the orphan GPCR, GPR55, first cloned in 1999 (Sawzdargo et al., 1999).

We did not study the effect of PAK1 on other PPARs as 5-ASA is a specific agonist for PPARγ [22], and only PPARγ but not PPARα or δ induces p65 degradation [23].

G1 is a specific GPR30 agonist that does not bind to the classical nuclear receptors [17] and that also activates the MAPK [44], [45] and PI3K signaling pathways [17].

63 The muscarinic acetylcholine receptor is a target for drug development; cevimeline is a specific MR3 agonist used in the treatment of sicca symptoms.

11 Varenicline is a specific partial agonist of the α4β2 nicotinic acetylcholine receptor, 12 which is effective in increasing abstinence rates among cigarette smokers.

We have previously found that methyl syringate is a specific and selective agonist of the human transient receptor potential channel ankyrin 1 (TRPand and suppresses food intake and gastric emptying in imprinting control region mice.