Sentence examples for be a shared pathogenic from inspiring English sources

Consistent with the idea that IFN pathway activation may be a shared pathogenic factor among these diseases, Niewold and colleagues found that serum IFNα levels were higher in five untreated JDM patients with a family history of SLE compared with 13 untreated patients without a family history of SLE [ 33].

The "telomeropathies" are related to each other due to a shared pathogenic mechanism of telomere shortening.

Initially, immunoreactive, ubiquitin-positive neuronal inclusions were identified in ALS and FTLD and provided a first clue of a shared pathogenic mechanism between these conditions.

It suggests there will be shared pathogenic pathways and the potential for shared therapies for these diseases.

Given that we have found that reduction in PICK1 can suppress both SCA3 and hAtx1-Q82 pathogenesin in flies, PICK1 may be involved in the shared pathogenic pathways.

The causes for the onset and manifestation of associated diseases are various: genetic predisposition, shared pathogenic mechanisms, and others are of unknown nature [5].

While certain autoimmune diseases share selected genetic, clinical and laboratory features, it is not clear if shared pathogenic mechanisms might link a number of SAID.

Since the unaffected siblings of the patients are expected to share pathogenic genes, those hypotheses need two lines of confirmation: (a) that the unaffected siblings of the patients have such advantages, and (b) that such advantages really contribute to sufficiently increase their reproductive fitness.

Microvascular and macrovascular complications of diabetes are thought to share pathogenic mechanisms.

Potentially, shared pathogenic pathways are also at play.

Thus developments of therapeutic interventions that are applicable across the broad spectrum of NDs and target the shared pathogenic mechanisms may offer the best hope for a future neuroprotective therapy.