Sentence examples for be a sensitive target from inspiring English sources

The Müllerian duct also proved to be a sensitive target of toxicity in frogs.

In conclusion, macrophages would appear to be a sensitive target for CTLA4-Ig treatment in RA.

It was concluded that the development of the HPA axis is affected by exposure to PCBs and that cortisol synthesis appears to be a sensitive target for POPs.

Given that some of these effects occurred at relatively low doses (< 1 mg/kg/day), this appears to be a sensitive target for MeHg's effects.

The immune system is a sensitive target to the toxic action of chemicals in several organisms [19, 30 32].

Collectively, these studies demonstrate that m-aconitase is a sensitive target of ROS generated in cells and tissue.

The CNS is a sensitive target organ for mercury vapor exposure, with the most consistent and pronounced effects [ 21, 65], although little is known about the distribution pattern in the human brain.

Mitochondrial DNA, in close proximity to the sites of oxygen radical production and unprotected by the histones that are associated with nuclear DNA, is a sensitive target for oxygen radical attack.

Alterations in regional brain concentrations of serotonin, dopamine, and norepinephrine have also been described by Bleavins et al. (1984), and a recent study has found that exposure to HCB can produce oxidative stress and that the brain is a sensitive target organ of HCB toxicity (Song et al. 2006).

The endothelium is a sensitive target of PM, and animals and humans exposed to PM show endothelial dysfunction (Brook et al. 2011) and EPC depletion (O'Toole et al. 2010), indicating that PM exposure potentially affects the endothelium by acutely causing direct loss of flow-mediated dilation and, in the long term, attenuating EPC-mediated endothelial repair and regeneration.

Although studies have demonstrated that the fetal mammalian heart is a sensitive target of TCDD-induced teratogenicity (Thackaberry et al. 2005), only in the past few years have toxicologic studies demonstrated cardiovascular effects after exposure to dioxins in adult rats and mice.