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An analysis of anatomical brain MRI data exhibiting cortical thinning, currently considered to be a sensitive early biomarker for neurodegenerative diseases, is used to illustrate the method.
Although behavior has been postulated to be a sensitive early indicator of exposure to certain environmental contaminants, no such research on the reproductive behavior of gestagen-exposed fish has been conducted to date.
However, microcirculation alterations in muscle and skin blood flow already occur during these early stages and measures of tissue cardiovascular reserve should be a sensitive early warning measure of impending cardiovascular collapse.
Neutrophil gelatinase-associated lipocalin (NGAL) is another LMWP, which is highly induced during inflammation and found to be a sensitive, early marker of acute kidney injury [ 35].
NGAL is considered to be a sensitive, early marker of acute kidney injury (acute tubular necrosis), i.e. of a state of extensive global injury of proximal tubular cells [ 35].
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Conclusion: Urinary GST-to-creatinine ratios are a sensitive early biomarker for renal injury after infrarenal abdominal aortic aneurysm repair.
However, NT-proBNP might be a sensitive and early marker that might only translate into functional and structural changes after more than 6 months of treatment.
The present study was undertaken to evaluate whether an overexpression of the heat shock protein (hsp 72 stress protein, which indicates repair of damaged proteins, could be a sensitive and early biomarker of environmental pollution by Cd.
Thermocouple time constant is found to be a sensitive parameter for early detection of the TIB.
There are few MRI studies in axial PsA but bone oedema appears to be a sensitive sign of early sacroiliitis.
Ultrasound measurement of renal perfusion could be a sensitive method for early investigation of cardiovascular and renal injuries.
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CEO of Professional Science Editing for Scientists @ prosciediting.com