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We also found that P48 expression can be a selection biomarker for receiving IFN-α treatment [ 29].
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Thus, Bif-1 expression may be a candidate biomarker for selection of adjuvant chemotherapy in stage II CRC.
Methane could also be a biomarker when all other biomarker gases become undetectable in a dying planet's atmosphere.
Based on the in vitro studies that show greater FGFR-dependence of the tumour cell lines with FGFR fusions than those with point mutations (2, 3), we suggest that the presence of a fusion protein may be a useful predictive biomarker in the selection of patients for FGFR-targeted therapy.
Serial monitoring of LBP serum levels may be an appropriate biomarker for subgroup selection and guiding of therapy.
While preliminary results from the phase I/II trial suggested that PD-L1 could be an appropriate biomarker for patient selection, subsequent analyses have shown numerous PD-L1-negative patients had responded to treatment with nivolumab, although lower rates are seen.
"It's most likely that it will be a panel of biomarkers".
From this perspective, AGR2 is a potential predictive biomarker enabling selection of an optimal algorithm for adjuvant hormonal therapy in postmenopausal ER-positive breast cancer patients.
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