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Therefore, TfR could be a relevant target for molecular targeted therapies against tumors.
The fibroblast growth factor receptor (FGFR) signaling pathways may be a relevant target in MPM.
Heaney et al [60] recently demonstrated that proteasome may be a relevant target for quiescent CML stem cells following tyrosine kinase inhibitor therapy, while proteasome inhibitor are capable of inducing CML stem cell specific apoptosis.
These data suggest that TSPO could be a relevant target for endozepines during inflammation and sepsis.
CLBP patients seem to be a relevant target group for PA promotion.
Primiparous women are particularly open to new advice and would be a relevant target.
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Cathepsin (Cat) K is a critical bone-resorbing protease and is a relevant target for the treatment of osteoporosis and bone metastasis, while CatS is an attractive target for drugs in autoimmune diseases (e.g. rheumatoid arthritis), emphysema or neuropathic pain.
The frequent expression in OSCC suggests that MIA2 is a relevant target for cancer treatment.
Therefore, suppression of cyclin D1 is a relevant target to combat cancer.
Overall, it appears that the proteasome is a relevant target for aging research.
Thymidine phosphorylase is a relevant target by being both an angiogenesis-promoting factor, and the intracellular activator of 5FU prodrugs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com