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The fragmentation of the Golgi ribbon is likely to be a regulated event during the differential of parietal cells.
However, necrosis is no longer considered to be an uncontrolled process, but necrotic cell death can also be a regulated event that contributes to the development and to the maintenance of tissue and organismal integrity [ 9- 11].
On the other hand, the cytoplasmic localisation of PR70/B β1 is in contrast with the reported nuclear localisation of its truncated PR48 form [ 20], suggesting that nuclear import/export of PR70 isoforms may be a regulated event.
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Interestingly, the examined tissues show very different expression patterns, suggesting that alternative splicing in this case is a regulated event.
Necrosis has long been considered an uncontrolled mode of cell death, but it has become clear that necrosis is a regulated event controlled by several enzymes such as the serine/threonine kinase RIP1 and the DNA repair enzyme poly(ADP-ribose) polymerase (PARP) [ 13].
This frequency suggests that switching is caused by a regulated event rather than by random mutations.
These results indicate that the unusual organization of individual Golgi stacks dispersed throughout the cytoplasm of these terminally differentiated cells is likely to be a developmentally regulated event.
Biofilm formation is a highly regulated event, and algC was reported as an alginate-producing gene that enhances the biofilm formation potential by fourfold and is positively regulated by the sigma factor (Kokare et al. 2009).
Degradation of IκB is a tightly regulated event that is initiated upon specific phosphorylation by activated IKK.
The mechanism underlying IP3R2 upregulation is not clear, but clearly is a transcriptionally regulated event.
Polyadenylation is a highly regulated event and alternative polyadenylation (APA) is one of the major contributors of transcriptome diversity [ 12, 13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com