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Our study suggests that miR-586 might participate in the occurrence of aGVHD and could be a putative target for novel aGVHD therapy.
Bioinformatics analyses predicted that Mdm2 might be a putative target gene of miR-509-5p miR-509-5p miR-509-5p
These findings suggest that miR-194 might be a putative target molecule for regulating metabolic and bone disease.
Nevertheless, our results strongly suggest a new and blossoming VEGF-driven processes in the bladder that may be a putative target in neuronal plasticity.
We found this sequence to be a putative target site for many binding motifs such as all MEF2 family members, HNF1.03, OC.2 and PAX4 (marked by ** in Table 1 and Additional data file 1).
Using bioinformatics analysis, RB1 gene was determined to be a putative target of miR-192 and luciferase reporter assays confirmed direct binding of miR-192 to the 3′-UTR of this gene [ 76].
Similar(48)
Although the antioxidant thioredoxin peroxidase (TPX) is a putative target exploited in vaccine studies of lymphatic filariasis, the high sequence homology with host peroxiredoxins remains a great concern.
As the crystal structure of this protein is known, it is a putative target for the structure-based design of inhibitors.
For example, estrogen receptor-alpha is a drug target for treating breast cancer, and 17-hydroxysteroid dehydrogenase (17HSD1) is a putative target for endocrine therapy of hormone-dependent breast cancer [23].
Further analysis of possible mechanisms revealed that the Bmi-1 oncogene was a putative target of miR-128a.
In our model, CFLAR, an NF-κB-inducible anti-apoptotic protein which inhibits caspase 8-mediated apoptosis, is a putative target of mmu-miR-146b and -223.
More suggestions(15)
be a personal target
be a putative tumour-suppressor
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be a putative mechanism
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be a putative methyltransferase
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com