Sentence examples for be a putative substrate from inspiring English sources

Recently, VEGFR-2 was reported to be a putative substrate of ST14 in HUVECs, resulting in ectodomain cleavage and inactivation of cell signaling [75].

The cleavage sequence in Ephrin receptor 2 is by analogy on the extracellular face of the membrane and therefore could be a putative substrate.

These observations suggest that Gab1 could be a putative substrate of PTP1B.

Interestingly ApoC-II has been shown to be a putative substrate for the metalloproteinases MMP-14 and MMP-7 (Kim et al, 2006).

The first reports on TamB assumed it to be a putative substrate of a two-partner secretion system, as secondary structure analyses clearly highlight an extensive region of the protein to encode beta-strands which are typical structural hallmarks of two-partner secretion system substrates (Stegmeier et al. 2007; Chaudhuri et al. 2010).

The fifth gene in this module (SAR1011) was a putative substrate binding protein for iron complex transport [ 32], which agrees with the functional relationship to the sst operon inferred from the network.

On the other hand R45 of PTP1B (equivalent to R312PTP-SL) is considered a putative substrate binding site [32].

Mei2 is a putative TOR substrate and potent meiosis-signaling molecule identified in the fission yeast Schizosaccharomyces pombe [ 13, 14].

Also, PHRF1 is a putative phosphorylation substrate of ataxia telangiectasia-mutated/ataxia telangiectasia and Rad3-related kinases; however, the role of PHRF1 in DNA damage response is unclear.

Based on structural comparison and functional complementation analyses, the active sites of SAICARs and AIRc were identified, including a putative substrate CO2-binding site.

The first was ATF-2, a putative substrate of p38 MAPK.