Furthermore β -actin has been shown to be a proper endogenous control in the analysis of KCNQ1 and KCNH2 expression level in patients with LQTS [ 3].
Pristine carriers are not a proper control (different size, charge, surface features, etc).. Carriers with ligands conjugated to PEG have shorter PK and different BD vs pristine PEGylated carriers.
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Hence, the active dumping site should be closed by a proper control with liner provision.
Their main drawback, the narrow domain of operating parameters, can be resolved with a proper control system.
Upcoming studies should be prospective, introduce a proper control and take the technical ONS challenges such as lead migration, frequent infections and proper blinding procedures into account.
One prerequisite to minimize corrosion is a proper oxygen control system (OCS) via the gas-phase to set the oxygen concentration in the liquid Pb Bi.
It is concluded that a proper control of the initial reactor temperature profile is critical for a safe reactor start-up while the impact of the other manipulated variables is relatively small in comparison to the effect of the initial reactor temperature profile.
The VB technique is applied to small bunch charges (0.5 15 pc) and it is driven with a proper control of the bunch density versus the bunch energy gain, which permits one to control the transverse beam emittance, the bunch length and the correlated longitudinal energy spread, in a peculiar manner.
