Sentence examples for be a primary pathophysiological from inspiring English sources
On the other hand, the enzymatic activity did not correlate with MMSE scores, signifying that it might be a primary pathophysiological sign and may predict disease onset [ 41].
Several studies suggested that axonal degeneration in the PNS including early loss of NMJs is a primary pathophysiological event in fALS mice [16], [17], [52], [53], [54].
Furthermore, evidence suggests that nerve terminal dysfunction in relevant brain regions precedes neurodegeneration and is a primary pathophysiological event in Alzheimer's disease (reviewed by Coleman et al. 2004; Forero et al. 2006; Keating 2008; LoPachin et al. 2008a; Selkoe 2002).
Expansion of adipose tissue during positive energy balance is a primary determinant of obesity and related pathophysiological sequalae.
Dysregulated inflammation and coagulation are central pathophysiological events in ALI and lung vascular endothelium injury is a primary cause of the alteration of the alveolar-capillary barrier leading to pulmonary oedema [159] [159].
The pathophysiological mechanisms for CTTH are only partly understood, and it has been debated whether mechanical pain sensitivity is a primary or a secondary phenomenon to CTTH.
In this concept, ACOTS, not DIC, is considered to be the primary pathophysiological mechanism of coagulopathy of trauma.
In type I diabetes (T1D), the established view has been that the primary pathophysiological event is β-cell apoptosis due to a β-cell specific autoimmune response, leading to profound β-cell deficiency.
Shunt-induced hypoxemia is considered the primary pathophysiological abnormality and main diagnostic criteria of acute respiratory distress syndrome (ARDS).
Insulin resistance and impaired insulin secretion are considered as primary pathophysiological factors in the development of T2DM [ 1].
The primary objectives of this study were to evaluate whether DNA damage accrual may be a pathophysiological mechanism of stem cell aging in humans that may contribute to the diminished functional capacity of aged stem cells to maintain tissue homeostasis.
