Sentence examples for be a primary mediator from inspiring English sources

In this study, we demonstrated that NKDCs, functioning as immunostimulatory DCs, could be a primary mediator of the α-GC-mediated immune response.

The neuro-endocrine system, with its hypersensitivity to various low dose phenomena, may be a primary mediator for the various energy emanations; however, the occasional rapid manifestations of symptoms from exceedingly small doses may indicate some other yet undefined communications pathway in living organisms.

Based on work in cultured cells, SHP-2 is thought to be a primary mediator of cytoskeletal disruption induced by CagA [24].

These data suggest that HMGB1 seems to be a primary mediator of trauma-induced pathology.

Activation of TLR4 signaling by endotoxin is believed to be a primary mediator of sepsis and septic shock, via excessive production of cytokines and proinflammatory mediators [ 1].

The latter are thought to be a primary mediator of neurotoxicity, and have also been postulated to underlie behavioral impairments in AD Tg mice [ 19].

α-Amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor is a primary mediator of fast glutamatergic excitatory signaling in the brain and has been implicated in diverse neuropsychiatric diseases.

Prophages are a primary mediator of GAS intra- and inter-serotype differences in virulence factor content [80].

Recently, we identified a gastrin-releasing peptide (GRP) system in the lumbar spinal cord that is a primary mediator for male reproductive functions.

Gli2 is a primary mediator of Shh signaling and mainly functions as a transcriptional activator [1], however, it was shown to have repressor functions in CNS and skeletal muscle development [10], [11].

While VEGF is a primary mediator of angiogenic responses, bFGF is also one of potent angiogenesis inducers to stimulate the vascular endothelial mitogenesis and is often involved in pathologic angiogenesis.