Sentence examples for be a powerful surrogate from inspiring English sources
In order to be a valid instrument for use in drug development, any therapeutic monitoring technique must be demonstrated to be a powerful surrogate for more important, but often more costly to obtain, measures of outcome including survival.
But he is expected to be no less a powerful surrogate for Clinton, particularly among the blue-collar voters comprising America's 'rust belt' and upon whom Trump's narrow path to the presidency is predicated.
The surrogate model is proven to be a powerful tool to aid in reduced physical prototype costs and product development time.
In particular, we used surrogate variable analysis which has been shown to be a powerful method for removing unwanted measured and unmeasured sources of heterogeneity [ 30].
Thus, endothelial dysfunction is a central feature of CV disease, and may represent a powerful surrogate marker in the development of new treatments for CV disease.
Pathological complete response is a powerful early surrogate of good survival in ER-negative and HER2-positive cancers, but its prognostic value is less important in ER-positive cancers because many patients with extensive residual cancer continue to do well probably because of the benefit from adjuvant endocrine therapy (von Minckwitz et al, 2012).
Anchorage-independent colony formation in methylcellulose is a powerful in vitro surrogate assay for tumourigenicity in xenograft assays.
The persistent presence of post-chemotherapeutic CTCs is a potential powerful surrogate marker for determining clinical outcome in stage III colon cancer patients receiving adjuvant mFOLFOX chemotherapy.
Galleria has emerged as a powerful, surrogate and ethically acceptable model host for human pathogens, but the lack of genomic data is a major impediment for its use in preclinical research.
If future controlled trials confirm that increased CMAP amplitude is a consistent marker of biologic response that correlates with improvement in motor function, then this outcome measure could prove a powerful surrogate biomarker for future clinical trials.
