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Molecular oxygen has long been recognised to be a powerful modifier of cellular radiation sensitivity.
Gouras et al. [ 17] observed increased apo-E immunoreactivity in Aβ42-immunoreactive neurons and suggested that apo E might be a powerful modifier of intraneuronal Aβ accumulation.
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HSF1, a heat shock-related transcription factor is also a powerful modifier of carcinogenesis by several factors, including PDGFB.
As proof of principle, 2-APB was used, a powerful modifier of the STIM1/ORAI machinery with several, complex target sites.
Dai C, Whitesell L, Rogers AB, Lindquist S. Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
Dai, C., Whitesell, L., Rogers, A. B. & Lindquist, S. Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
Although HSF1 is not an oncogene, increasing evidence has demonstrated that it is a powerful multifaceted modifier of carcinogenesis.
In conclusion, the current study confirms that TM6SF2 is associated with histologically defined NAFLD, and is the first demonstration that this gene serves as a powerful modifier of hepatic fibrogenesis.
The identification of modifier genes is a powerful means to dissect molecular pathophysiology, discover mechanisms underlying neurodevelopmental phenotypes and provide additional targets for drug development.
Individual patient data meta-analysis is a powerful method of evaluating effect sizes and exploring treatment effect modifiers.
He is a powerful, powerful drummer.
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