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pS6Ser240/4 may be a potential predictive biomarker for everolimus, which requires validation.
Increased inflammatory markers, such as C-reactive protein (CRP), might also indirectly reflect inflammatory muscle injury and could be a potential predictive marker of subsequent Myo-SSc occurrence.
A number of studies also demonstrated higher RDW levels to be a potential predictive and prognostic marker in coronary and peripheral arterial diseases [ 11, 18, 19].
Our results suggest that phospho-p90RSK expression, which reflects the tumor's Ras/Raf/ERK/p90RSK pathway activation can be a potential predictive marker for chemotherapy response in ER-positive breast cancer which needs further independent validation.
Interestingly, SDC1 expressing breast carcinomas show decreased response to chemotherapy [ 34], whereas it has also been indicated that the loss of SDC1 expression may be a potential predictive factor for response to preoperative systemic therapy [ 35].
In conclusion, we identified that the gain of IL-7 is associated with cisplatin resistance, suggesting that IL-7 might be a potential predictive marker of cisplatin resistance in glioma patients.
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Th17 are a potential predictive factor of therapy response [ 72].
These findings suggested that a high survivin expression level was a potential predictive biomarker of UBC prognosis.
The multivariate analysis showed that a high survivin expression level was a potential predictive biomarker of poor overall survival (P = 0.02).
From this perspective, AGR2 is a potential predictive biomarker enabling selection of an optimal algorithm for adjuvant hormonal therapy in postmenopausal ER-positive breast cancer patients.
Taken together, the results of our present study suggested that a high survivin expression level was a potential predictive biomarker of UCB progression and poor prognosis.
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