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These results demonstrated that, at the least, this variant could be a potential pathological mutation for this family.
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Interfering with these functional interactions seems to be a potential way of antagonising the target protein's pathological role.
Our findings reveal pathological SF-1 up-regulation to be a potential mechanism enhancing local oestrogen synthesis in LCTs, suggesting this mechanism to be explored as a potential cause of CYP19 up-regulation in other pathological conditions as well.
Custom 3D printing an individualized ossicular prosthesis would be a potential solution for the range of anatomic variation encountered in the pathological middle ear.
Aberrant cell-cycle re-entry of neuronal cells is emerging as a potential pathological mechanism in AD.
Aberrant neuronal re-entry into the cell cycle is emerging as a potential pathological mechanism in Alzheimer disease (AD).
The obesity-associated risk allele has been shown to have a potential pathological effect on brain volume: healthy elderly subjects with the risk allele had brain volume deficits (average differences of 8% in frontal lobes and 12% in occipital lobes) compared with non-carriers.
Thus FGF signaling is a potential therapeutic target for pathological angiogenesis in chronic inflammatory diseases.
Thus the level of Aβ42 production in the brain, especially relative to total Aβ production, is a potential biomarker of the pathological process in AD.
As sex is a potential influencing factor of both pathological and non-pathological phenotypes, gene expression analyses that do not account for sex-specific effects could fail to identify a significant proportion of genes that contribute to the condition under investigation (Ober et al., 2008).
It is a potential therapeutic target in many pathological conditions, including thrombosis and cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com