Sentence examples for be a potent suppressor from inspiring English sources

hA3G has been shown to be a potent suppressor of MLV infection in several studies [11], [27], [29], [35], [38], [47].

Fucoidan protected hepatocytes from BA-induced apoptosis and preferentially inhibited invasion of HCC cells by up-regulating p42/44 MAPK-dependent NDRG-1/CAP43, suggesting it may be a potent suppressor of tumor invasion with hepatoprotective effects.

In C elegans, serotonin has been shown to be a potent suppressor of striated muscle degeneration, with serotonin being more efficient than prednisone, a palliative treatment against DMD, in blocking the muscle degeneration.

Mechanistically, NET formation in neutrophils may depend upon the activation of the extracellular signal-regulated kinase (ERK) (Hakkim et al., 2011, Yoo et al., 2014), and selective inhibition of ERK has been demonstrated to be a potent suppressor of NETosis (Hakkim et al., 2011).

Similarly, while TorsinA was found to be a potent suppressor of α-synuclein aggregation and toxicity in cellular models [ 79] and in a Caenorhabditis elegans model [ 93], an elegant recent study using both an MPTP-induced mouse model of PD and α-synuclein transgenic mice could not detect a neuroprotective effect for overexpression of TorsinA [ 94].

The AuNPs were a potent suppressor of virulence of the plant pathogenic fungus Alternaria solani.

Palmitate is a potent suppressor of proinsulin and general protein synthesis in β-cells (Figure 5).

Furthermore, ATP may not induce calcium release in all cell types, given that ATP is a potent suppressor of calcium activation in hippocampal neurons [40], [41].

Previously, we have shown that TRKB is a potent suppressor of anoikis and that TRKB-expressing cells form highly invasive and metastatic tumors in nude mice.

Previously, we have shown that TRKB is a potent suppressor of anoikis (apoptosis induced by inappropriate or absent cell adhesion) in rat epithelial cells, and that TRKB-overexpressing cells form highly invasive and metastatic tumors in nude mice [24].

Moreover, p53 is a potent suppressor of IGF-1 signaling at multiple points [28], which may in part explain reduced IGF1 signaling observed in the XpdTTD mice (see below).