Sentence examples for be a potent repressor from inspiring English sources
We were intrigued by these data, because Su z 2 is a functional homolog of the PcG protein Psc, and known to be a potent repressor when targeted to loci by LexA fusion [29], [36], [37], [38].
Rapamycin has been shown to be a potent repressor of translation; both microarray and proteomic analyses have demonstrated that rapamycin significantly decreases translation of mRNA-encoding initiation factors and ribosomal proteins (Grolleau et al., 2002; Guertin et al., 2006).
ComK synthesis is regulated by a series of reactions that involve quorum sensing; SinR is one of the activators in this cascade, acting negatively on rok transcription [ 35], and is known to be a potent repressor of biofilm formation [ 36].
The zinc-finger transcription factor Snail is a potent repressor of E-cadherin and induces EMT.
Thus, SAHA is a potent repressor of FLIP expression in mesothelioma and is significantly more effective in this regard than the current standard-of-care, cisplatin.
COUP-TF is a potent repressor that antagonizes transcriptional responses mediated by other nuclear receptors including HNF4, PPAR, ER, RAR and VDR [ 66].
To summarize, we have shown that miR-142 is a potent repressor of cytokine signalling in the myocardium, and this miRNA must itself be repressed in order for adaptive cardiac hypertrophy to take place.
miR-133 belongs to a group of myomiRs (muscle-specific miRNAs) and is a potent repressor of non-muscle genes, thereby playing a role in embryonic stem cell differentiation and muscle specification [ 29, 30].
The authors also demonstrated that the 5-HT2A/B anterugide terugise is a potent repressor of fibroblast TGFβ1 expression and when administered in vivo the drug improved lung function and decreased fibrosis when applied in a therapeutic regimen to mice with established bleomycin-induced lung disease.
In contrast with Rev-Erb α/β, which represses transcription, our results demonstrated that E75 is neither a potent repressor nor a strong activator but potentiates the activation of per transcription by UNF.
