Sentence examples for be a potent mediator from inspiring English sources

Furthermore, IL-10 levels were strongly related (r = 0.87, p < 0.005) to TNF-α immediately following both SIT sessions, which is not surprising, as IL-10 has been shown to be a potent mediator of TNF-α [1, 7].

The NGF/TrkA system is known to be a potent mediator of pain [5].

Though the MTDH gene was cloned only 5 years ago, this novel gene is now known to be a potent mediator in the development of malignancies and component of oncogenic signaling pathways.

Our screen identified a cell adhesion molecule PVRL4 (poliovirus receptor-like 4), also known as Nectin-4, which we demonstrate to be a potent mediator of anchorage-independent colony formation in normal epithelial and cancer cells alike.

HuHMFG1 has been demonstrated to be a potent mediator of ADCC by recruiting natural components of the body's immune system (Snijdewint et al, 2001) HuHMFG1 binds to the extracellular MUC1 peptide sequence, PDTR.

Although COUP-TFI is suggested to be a potent mediator of cancer progression, little is known about the endogenous targets of this orphan nuclear receptor in breast cancer cells.

Interleukin 8, also known as CXC chemokine ligand 8 (CXCL8), is a critical chemokine in the recruitment of leukocytes to sites of infection and is a potent mediator of inflammation.

Vascular endothelial growth factor (VEGF), a multifunctional cytokine that promotes angiogenesis and is a potent mediator of microvascular permeability, which is critical for the development of diabetic retinopathy (DR).

Importantly, MAb A32 was a potent mediator of ADCC activity.

PAF is a potent mediator of anaphylaxis and inflammation and is also implicated in shock, graft rejection, renal diseases, ovoimplantation, and certain disorders of the central nervous system (Küster et al. 1986; Dive et al. 1989).

Both IL-6 and IL-10 have been shown to be associated with stimulation of the Th2 pathway and activation of anti-inflammatory cascades, and they may also inhibit TNF-α, which is a potent mediator of tissue damage [12, 23 25].