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As noted, if the effects of IT BoNT B were uniformly expressed on all releasing functions of the peptidergic neurons, then we would expect that there would be a potent effect upon the release of other transmitters, notably glutamate.
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In contrast, the underlying mechanism of terminated haemorrhage after vasopressin may be a potent vasoconstrictory effect via V1 receptors and therefore reduced blood flow in skin, muscle, fat tissue and gut.
As reported in Cuccurazzu et al. [ 135] ALC proved to be a potent proneurogenic molecule, whose effect on neuronal differentiation of adult hippocampal neural progenitors is independent of its neuroprotective activity.
Thus, CORM-2 appears to be a potent inhibitor of negative effects of hepatic I/Ri, while at the same time having no appreciable negative effects on the respiratory system.
A humanized rat monoclonal anti-RAGE antibody that antagonizes RAGE interactions with multiple ligands was shown to be a potent protector against the toxic effects of sepsis [23].
BCL2 is well-known to be a potent prosurvival advocate with antiapoptotic effects (11).
Contrast-enhanced ultrasound may be a potent tool for assessing the effects of anti-angiogenic treatment in patients.
This glycoprotein has been shown to be a potent immune stimulator with positive effects on the generation of cytotoxic effector cells (NK/LAK) from human peripheral blood mononuclear cells (PBMC) [ 41, 42].
IL-10 may be a potent anti-inflammatory cytokine, achieving the effect through suppression of TNF-α, IL-6, and IL-1 production by activated macrophages [ 38].
On the other hand, VE is proved to be a potent antioxidant which ameliorates the adverse effects triggered by DM.
VEGF is considered to be a potent, multifunctional cytokine with important biological effects on the vascular endothelium [ 13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com