Trafficking of G protein-coupled receptors (GPCRs) to the plasma membrane is a pivotal process to fulfill their biological functions.
Angiogenesis is a pivotal process of homeostasis and tissue repair, but it also favours neovascularisation syndromes and cancer nutrition.
Secretory granule biogenesis is a pivotal process for regulated release of hormones and neurotransmitters.
Placental angiogenesis is a pivotal process for efficient fetomaternal exchanges and placental development.
Encystation is a pivotal process in the life cycle of E. histolytica and is indispensable for its transmission.
Angiogenesis is a pivotal process in osteogenesis, which regulates cell proliferation, differentiation, and bone formation and resorption.
The differentiation of macrophages to lipid-laden foam cells is a pivotal process in the development of the atherosclerosis [ 31].
Migration is a pivotal process for both invasion and metastasis allowing cells to change position into tissues or metastasize to distant organs [ 5, 26].
It is readily accepted that PTM is a pivotal process conveying environmental stresses to physiologically diverse processes such as cell cycle regulation, growth, autophagy, and apoptosis (7, 35, 79).
Placental angiogenesis is a pivotal process that establishes fetomaternal circulation, ensures efficient maternofetal exchanges, plays a key mechanistic role in the elaboration of the placental villous tree, and contributes to the overall development of the placenta throughout pregnancy.
