Sentence examples for be a pathological component from inspiring English sources

The impaired CREB phosphorylation in hippocampus may be a pathological component in neurodegenerative disorders [ 42, 43].

As alcohol dependence develops, the stress response systems are upregulated, and this hyperactivity may in fact be a pathological component of dependence (Koob 2008).

α-Synuclein is a pathological component of PD by participating in the Lewy body formation as the major constituent [8], [9].

Mitochondrial dysfunction is a pathological component of neurodegenerative diseases [ 53], as well as when cells are encountering various stressors [ 41].

Tumor associated neo-angiogenesis is considered to be a necessary pathological component of tumor growth and a viable target for therapeutic intervention.

Since BMP signalling is important for distal axonal function, we propose that dysregulation of BMP signalling could be a unifying pathological component in this endosomal group of HSPs, and perhaps of importance in other conditions in which distal axonal degeneration is found.

In addition, lung fibrosis is a serious pathological component of systemic sclerosis [44] and can also be caused by a variety of medications (e.g. methotrexate) [45] as well as radiation therapy to the chest [46].

ASM proliferation and migration is a major pathological component in airway remodeling of asthma.

Insufficient angiogenesis is a major pathological component of diseases such as chronic wounds and ischemic heart disease.

TAR DNA binding protein (TDP-43), encoded by the TARDBP gene on human chromosome 1, is a major pathological component of the neuronal inclusions associated with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP) [ 28].

Hypertrophic scars are a pathological process characterized by an excessive deposition of extracellular matrix components.