Sentence examples for be a null mutation from inspiring English sources

The mutation deletes several exons (Figure 1C) and is a likely to be a null mutation.

(iii) The Edardl-J allele may not be a null mutation.

The p.S205LfsX29 mutation results in lack of the nuclear localization signal and appears to be a null mutation.

The particular alleles involved in the cross were Atss2-1 and Atss3-1, previously shown to be a null mutation [ 29].

Although levy was previously suggested to be a null mutation (of Cox6a), we also tested the effects of Cox6a knockdown by RNAi.

The mg455 allele is a nonsense mutation that is predicted to result in truncation of SGK-1 within its kinase domain (Soukas et al., 2009); therefore, this is likely to be a null mutation.

Previously, we reported that the patient-specific recessive mutation hBest1 P274R is a null mutation due to structural disruption16, and the complete loss of Ca2+-dependent Cl− current in the hBest1 P274R iPSC-RPE was rescued by virus-mediated supplementation of WT hBest116.

These data clearly demonstrated that the mutation involved in the tw mutant was a null mutation for POMT activity.

As shown in Figure 1C, Cthrc1 RNA was absent in E16.5 Cthrc1-null embryo, indicating that the mutation was a null mutation.

Wild-type GPR126 transcript could not be detected in homozygous embryos (see below), suggesting that the targeted allele is a null mutation (Fig. 2c).

The trx-1 ok1449) trx-1 ok1449in this study is allele musedinn: a delethis in the coding region preventing transtudyon of the proteis (Table S1; [9]).