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Neointimal hyperplasia may, in part, be a normal cellular response to an abnormal (turbulent) flow environment.
Glaunsinger suspects that PABP relocation may actually be a normal cellular reaction to certain types of stress.
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Li, W. et al. Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Because NMD is a normal cellular process in eukaryotes, the approach should be generally applicable, as with RNAi.
Clinical issue Epithelial-mesenchymal transition (EMT) is a normal cellular process that generates three-dimensional structure in the embryo.
112 An alternative explanation may be that cell dissemination is a "normal" cellular process in that even normal cells disseminate at a certain rate.
This up-regulation is a normal cellular response to reduce the resulting oxidative stress, thus implying the occurrence of oxidative stress of GTT treatment in the present study.
In connective tissues, endothelin participates in stimulating the formation of myofibroblasts (the myofibroblast is a specialized type of fibroblast that is a normal cellular constituent of healing tissues) and increases levels of CTGF and matrix proteins [ 4].
Although apoptosis is a normal cellular process in organ morphogenesis (Coles et al. 1993; Kollros and Thiesse 1985; Pexieder 1975), we uncovered a significant increase of apoptosis in the midbrain and pronephric kidney over controls.
Although MG is a normal cellular constituent, its excessive production is deleterious (plasma MG levels are raised to around 800 nmol/l in young diabetics compared to about 400 nmol/l in young non-diabetic subjects, (Han et al. 2007)).
The pathway activated by toxicants such as lead, paraquat, and methylmercury is a normal cellular regulatory pathway; however, according to the authors, these agents "are just activating it inappropriately".
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