Sentence examples for be a negative modulator from inspiring English sources

These data suggest that CAST may be a negative modulator of BMD and a downstream target of BMP2 in modulating CAST mRNA expression of osteoblasts.

The first gene, BAX, is reported to be a negative modulator of autophagy only in the experimental context of dual BAK1 and BAX knockdown;, hence, negative modulation of autophagy by BAX may occur only in that rare genetic context, which may not occur frequently in clinical tumors.

Above the threshold (11/30), it was considered to be a negative modulator [ 72].

A score of < 75/95 was considered to be a negative modulator [ 56].

A score of 2 or more was considered to be a negative modulator [ 51].

A Body Mass Index (BMI) of more than 30 was considered to be a negative modulator [ 68, 69].

Charest-Marcotte A, Dufour CR, Wilson BJ, Tremblay AM, Eichner LJ, Arlow DH, et al. The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions.

PLK-1 is a negative modulator of p53 activity but has not been shown to affect its levels [32].

Since PLK-1 is a negative modulator of p53, inhibition of PLK-1 would relieve the negative regulation on wild-type p53 and potentially restore its transactivation and apoptotic functions.

Moreover, it was seen that Sirt-1 is a negative modulator of adipogenesis by docking with the nuclear receptor co-repressor (NcoR) [9] and induces a decrease of pro-inflammatory cytokine release [10] and a promotion of carcinogenesis [11] by the negative control of Nuclear factor-kB (NF-kB).

The data suggest that pregnenolone sulphate is a negative modulator of TRPC5 channels.