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The most extreme case will be a mutant causing females not to fertilize any of their eggs (n = 0).
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White eye color is a mutant phenotype, caused by a mutation in a gene in the pigment pathway, discovered in 1910 by the father of modern genetics, Thomas Hunt Morgan Greenn 2010; Morgan 1910).
Slow development was isolated from family 61, which is a physiological mutant caused by a conditioning lethal allele of the sw gene called swx [32], [33].
We have shown that the GM077 rice is a waxy mutant caused by down-regulation of GBSSI.
The results are consistent with an autosomal dominant mutant causing the white phenotype.
TerC was shown to be involved in adherence since a terC mutant caused a significant decrease in adherence to HEp-2 and IPEC-J2 cells by EHEC O157 H7 strain 86-24 [62]. 86-24 [62]
Second, a large number of genes are misexpressed in individual mutants causing an abundance of upregulated genes that are not miRNA targets [21], [22].
To investigate whether the different Se levels in TRα1+m mice were a defect caused by the mutant TRα1 acting during embryonal development or a direct consequence of the TRα1R384C aporeceptor activity, we exposed the mutant mice to elevated levels of TH pre- and postnatally, thus reactivating the mutant receptor specifically in these periods (18).
To investigate if the reduced level of dMyc protein in lgl mutant cells could be a cause of their elimination from the epithelium, we took advantage of the MARCM system [ 26] to express the UAS-dmyc construct [ 27] in lgl-/ clones.
Huntington's disease (HD) is a neurodegenerative disease caused by mutant huntingtin protein containing an expanded polyglutamine tract, which may cause abnormal protein protein interactions such as increased association with calmodulin (CaM).
Our findings provide additional support for the role of Hwp1 in oral infection, and in addition argue that the reduced expression of HWP1 in the bcr1/bcr1 mutant is a major cause of the mutant's oral epithelial biofilm defect.
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