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Whereas in other cell types, most notably neuroendocrine cells, exocytosis is thought to be a multistep pathway that culminates in the (high) Ca2+-triggered fusion of secretory vesicles with the plasma membrane, little is known about those 'pre-fusion' steps in platelets.
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Signaling across long distances is a multistep pathway [ 13].
MMR is a multistep pathway comprising mismatch recognition, strand discrimination, strand removal and DNA resynthesis [ 40].
The auction will be a multistep process aimed for completion in the late fall.
Whatever ultimately comes of funding the border wall, it will be a multistep, multiyear process.
In the stage of molecular studies, oncogenesis of UM is considered to be a multistep, complicated process due to excessive acquired or inherited genetic alterations that result in abnormal regulation of multiple key cellular pathways [18], [19].
Ovarian carcinogenesis is believed to be a multistep process.
Briefly, miRNAs are processed in a multistep pathway.
Lignin is comprised of the monolignol subunits of p-coumaryl alcohol, sinapyl alcohol, and coniferyl alcohol that are the products of the a multistep pathway derived from phenylalanine Cinnamyl alcohol dehydrogenase (EC 1.1.1.195) catalyzes the final step in monolignol biosynthesis [17].
Lipopeptides are synthesised by means of a multistep pathway mediated by various non-ribosomal peptide synthetase (NRPS) enzymes which catalyse the condensation and selection of amino acid residues to yield various metabolites.
Pro-MMP-2 is activated at the cell surface through a multistep pathway that involves MMP-14 (MT1-MMP) and the tissue inhibitor of metalloproteinases 2 (TIMP-2) [46].
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