The leukocyte specific protein 1 or LSP1 is a multi functional protein involved in such divers biological processes as the regulation of neutrophil motility, chemotaxis, adhesion and membrane immunoglobulin M (mIgM) mediated apoptosis of B-lymphocytes.
Presently, it is unclear whether all these reported activities reflect splicing dependent or independent functions and whether Prp19 might be a multi-functional protein that interacts with distinct groups of proteins to carry out different functions.
UCH L1 appears to be a multi-functional protein that might contribute to more diverse cellular processes than were previously thought.
WRN appears to be a multi-functional component in various processes, including DNA replication, recombination, repair, and telomere maintenance, possibly through interacting with different proteins [12].
Therefore, BLM is likely to be a multi-functional protein involved in several aspects of genome maintenance in mammals.
26S protease regulatory subunit 6A (GI: 48101907) appears to be a multi-functional protein and it is not clear which of its roles might be relevant in HB.
Hepatocyte growth factor (HGF) has been proved to be a multi-functional peptide growth factor, which plays important roles in lung development, lung inflammation, and repair [ 1].
TGF-β has been recognized to be a multi-functional growth factor involved in regulation of such processes as development, wound healing, fibrosis, carcinogenesis, angiogenesis, and immunity [ 22– 24], and also to play a critical and double role in the progression of cancer [ 25, 26].
Visceral adipose tissue is a multi-functional organ with endocrine, metabolic and immunological functions and is demonstrated to have enhanced pro-inflammatory and pro-tumorigenic properties, when compared to subcutaneous fat depots [ 8].
Based on these results, we suggest that TkBCP is a multi-functional DNA-binding protein which has DNA chaperon and antioxidant functions.
As described above, it has been suggested that CRBN is a multi-functional, stress response protein.
