Sentence examples for be a molecular null from inspiring English sources
Homozygous iv52 animals have the same phenotype as hlh-6 (tm299 ) homozygotes, which carry a deletion allele predicted to be a molecular null (Smit et al. 2008), and iv52 fails to complement hlh-6 (tm299 ).
Df50 is a molecular null allele denoting a large deficiency that deletes nearly the entire daf-16 coding region [ 6].
mtrm is a molecular null allele (Xiang et al. 2007); in all crosses, mtrm was introduced into the analyzed genotypes via the male because this stock is contaminated with Wolbachia, a maternally transmitted intracellular bacterium (Serbus et al. 2008).
The tm593 deletion allele is a molecular null, as confirmed by RT-PCR analysis, which revealed that only very short (<37 amino acids), truncated forms of the protein are generated in tm593 animals, which do not contain any of the DNA-binding Zn-fingers (see File S1).
The daf 16(mu86) allele, an 11 kb genomic deletion that removes nearly all of the winged-helix domain, is a presumed molecular null.
It is a molecular test that, until recently, was confined to molecular biology laboratories.
In short, I am a molecular biologis.
These observations show that ok578 and tm653 are molecular null alleles.
The molecular defect in the scat allele has not been reported, and so it may not be a null allele.
Phenotypic and molecular studies suggest that notch3 zm is a null or near-null mutation, and that notch3 st51 is a hypomorphic allele that probably retains weak notch3 function.
