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PPARgamma was shown to have a key role in adipogenesis and proposed to be a master controller of the "thrifty gene response" leading to efficient energy storage.
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The other controller in the cascade is a master controller that adjusts the set point of the slave controller.
mTORC1 is a master controller of protein synthesis, integrating signals from growth factors within the context of the energy and nutritional conditions of the cell.
PGC-1β is a master controller of hepatic energy homeostasis in part through regulation of mitochondrial oxidative metabolism genes.
40, 41 CREB-regulated PGC-1 α is a master controller of mitochondrial biogenesis and antioxidant proteins associated with maintaining mitochondrial membrane integrity.
Since ATM (as well as DNA-PKcs) is a master controller of DDR, determining the specific downstream pathway regulating radiosensitivity is critical for development of inhibitors.
As most molecular responses to Pi starvation are affected in phr1 mutant, PHR1 has been considered a master controller of Pi signaling pathway [ 16, 19].
Be a master of stealth.
Next, mapper intermediate outputs are collected by a master controller and grouped by their key values.
Here, the 2-DOF haptic device and the X Y stage are employed as a master controller and a slave system, respectively.
Therefore, Spo0A is considered as a "master controller" for solvent production in C. acetobutylicum[ 72].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com