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Isobutanol is known to be toxic to microbial cells (Brynildsen and Liao 2009) and this feature can be a major restriction to improve productivity.
The cost of genotyping increases as more markers are included in the genotyping arrays and this could be a major restriction for large-scale application of genomic evaluation.
Besides the environmental concerns, the availability of freshwater resources may be a major restriction to companies wanting to extract shale gas commercially, especially where resources are already limited (Mangmeechai et al. 2013).
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Hitch Hiker uses a single meta manager in infrastructure mode for the creation of data aggregation overlay, which is a major restriction.
Radioresistance is a major restriction for the management of NPC.
That the dissipative loss of energy due to ohmic resistance of the pore water is not a major restriction for freshwater cable bacteria and electrogenic processes is evident from the electric potentials measured in the sediments.
For the qualitative study, recruitment was also a major restriction despite diligent attempts.
In addition to primary care, associated costs such as transport and time to seek treatment are also a major restriction on the poor for malaria control [ 16].
Among the groups that are most enthusiastic about the proliferation of low emissions zones is the electric vehicle industry, because the restrictions could be a major catalyst for development of the technology.
Diet and fluid management can reduce mortality, serious comorbidities, and debilitating symptoms in patients on hemodialysis, but restrictions may also be a major burden, and nonadherence remains high.
Abolishing restrictions on foreign ownership of local banks would be a major step.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com