Sentence examples for be a major regulator from inspiring English sources

To derive an explanation for the observed differences in starch metabolism, which has previously been suggested to be a major regulator of plant growth [ 51], the regulation of both starch synthesis and degradation has to be considered.

Significantly, the PI3K pathway, which is negatively regulated by PTEN, was also shown to be a major regulator of trastuzumab sensitivity in the clinic, underscoring the utility of the in vitro genetic screens to identify drug modulators.

More generally, triiodothyronine (T3) thyroid hormone is considered to be a major regulator of mitochondrial activity [ 33] and has been shown to regulate the expression of a number of COX subunits, inducing functional increases in COX enzyme activity [ 34].

Since NF-κB is known to be a major regulator of innate immunity and these cytokines have been found to be up regulated by NF-κB, our finding of significant elevation of this transcription factor becomes even more relevant.

Mechanical stiffness of ECM, in particular, is found to be a major regulator for the multiple aspects of cellular function.

Nitric oxide (NO) is a free radical known to be a major regulator of vascular tonus, to inhibit cell proliferation, induce apoptosis, and be a mediator of macrophage cytostatic and cytotoxic effects.

These results suggest that the FucT-VII may be a major regulator of the biosynthesis of the sLex-epitopes on T lymphoblasts, and this cell-based assay may be utilized for a screening system of FucT-VII inhibitors.

These findings suggested that TRY is a major regulator regulating trichome cluster formation, CPC is a major regulator regulating root hair and trichome formation, whereas TCL1 is a major regulator regulating trichome formation on inflorescence stems and pedicels.

SREBP1, which is negatively regulated by AMPK, is a major regulator of fatty acid synthesis [ 32].

These results suggest that besides regulating alginate production and chemotactic motility, AmrZ is a major regulator of iron homeostasis.

Phosphodiesterase 3A (PDE3A) is a major regulator of cAMP in cardiomyocytes.