Sentence examples for be a major modulator from inspiring English sources

Although many signaling pathways have been implicated in the regulation of cell migration and invasion, TGFβ is known to be a major modulator of tumor cell migration 1 and invasion, 42 partly due to its promotion of EMT.

Although the sample size of our study was small, these data suggest that sclerostin levels could be a major modulator of Wnt signaling in AD with implications in T2DM patients.

The chemokine receptor CXCR2 is a major modulator of inflammation, angiogenesis, tumor growth, and wound healing [1] [8].

Because FAK is a major modulator of angiogenesis, we examined the status of FAK in transfected meningioma cells along with irradiation.

As Pfmdr-1 is a major modulator of resistance to these drugs [10], monitoring in the future in which measure the high proportion of Pfmdr-1 mutants observed in Madagascar can have an impact on the resistance of these antimalarials, even if at the moment this impact seems modest [11].

It has been known that sleep is a major modulator of hormonal release and glucose regulation [ 38].

Ethylene is a major modulator of many processes in plants, including regulation of defense responses to pathogen attack [ 9].

Recently cyclin-depedent kinase 5 (CDK5) was identified as being a major modulator of bortezomib sensitivity in both MM cell lines and patient tumour cells.

The changes in CYP450 enzyme activity may affect the metabolism of various drugs; hence, they are a major modulator of adverse drug interactions.

To conclude, our study proves that Caveolin-1 is a major modulator of the TGF- β pathway (illustrated in Figure 4f).

As nutrition is a major modulator of global and cellular metabolism, it becomes apparent that nutritional interventions may impact cancer progression.