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The latter may yet be a major marker of marginalization and social exclusion and in some populations require interventions well beyond the health sector.
26 27 Faecal microbiome analyses have revealed a seemingly consistent association between disease and a reduction in the observed or estimated number of species in a sample, suggesting bacterial richness to be a major marker for gut health.
Species richness is proposed to be a major marker for gut health because of the idea that high bacterial richness and diversity often reflect ecosystem stability and resilience together with the consistent association between disease and a reduction in the number of species in a faecal sample.
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Proteinuria is a major marker of the decline of renal function and an important risk factor of coronary heart disease.
HER2 is a major marker of aggressive breast cancer and an important pharmaceutical target [ 28, 46].
Either way however, it is likely that having a smoking friend is a major marker of being a smoker oneself.
(b) Adipose tissue remodeling: Macrophage infiltration is a major marker of local inflammation in the adipose tissue in obesity.
Besides, as a control for experimental reliability, we performed the same analysis on the CDKN2A gene, which is a major marker of MM-associated CNAs [ 9], obtaining results in agreement with what expected from the literature (Additional file 2: Figure S1).
LOH at BRCA2 does not therefore appear to be a major prognostic marker in sporadic breast cancer.
This should not be a major influence on markers with shorter half-lives, such as measures of endothelial function.
Thus, nestin is also a major marker of regenerating tissue.
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