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In November when ITV finally bought out the last remaining GMTV minority shareholder, Disney, and took editorial control, it was clear there would be a major changing of the guard, on and off screen.
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End with Bilbo's choosing to go on an adventure (because this is a major changing point for the character).
"It really is a major changing of the guard, and this is the end of the Kennedy dynasty," Darrell M. West, a Brookings Institute scholar and author of "Patrick Kennedy: The Rise to Power".
The mid-August attack by Palestinian militants that killed eight Israelis near the southern city of Eilat, close to the Egyptian border, followed by Israeli airstrikes on Gaza and Palestinian rocket attacks from Gaza, proved to be a major interruption, abruptly changing the public discourse back to the more familiar mode of Israeli security in hostile surroundings.
This seems to be a major step towards changing the complex endeavor of education with AI.
Side effects associated with AED could be a major reason for changing drugs or to consider a referral for surgical management.
The company said it hopes this will be a major liftoff in changing its day-to-day operations.
Moreover, some studies have shown that the presence of a significant somatic disease in a parent effects on adolescents' development and psychosocial functioning [ 28, 29] and the diagnosis of a severe physical disease may be a major life-changing event for both patients and their children [ 30, 31].
Picking up "House of Cards" would be a major move by Netflix, which is gradually changing from a DVD-by-mail service to an online library of films and TV programs.
Because a career change is a major life-changing event, an internship is as much about convincing yourself that it is the right thing to do as it is about obtaining the skills and lingo to convince employers to hire you.
But the unlimited-ride MetroCard has been a major factor in changing how riders use the system.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com